Granulocyte Function in the Chediak-Higashi Syndrome of Mice
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منابع مشابه
Granulocyte function in the Chediak-Higashi syndrome of mice.
Granulocyte function was evaluated using activity of S. aureus and group D strepperitoneal exudate granulocytes from a tococcus by CHS cells through 90 mm of instrain of beige mice with the Chediak-Hicubation. The bactericidal defect was most gashi syndrome (CHS). Defective granupronounced at early time periods and was locyte chemotaxi of CHS cells (43% related to impaired intracellular killing...
متن کاملPlatelet function in the Chediak-Higashi syndrome.
Platelet function studies were performed on two patients with the Chediak-Higashi syndrome, one of whom had a history of easy bruising unrelated to thrombocytopenia. Both patients had prolonged bleeding times, abnormal platelet aggregation, and a defect of platelet storage granules, manifested by reduced platelet ADP, an increased ATP/ADP ratio, increased adenine nucleotide specific radioactivi...
متن کاملGranulocyte chemotaxis in the Chediak-Higashi syndrome of mink.
Studies of granulocyte chemotaxiswere Higashi mink generated normal performed in mink with the Chediakamounts of chemotactic factors. The Higashi syndrome. In vivo migration cellular defect in leukocyte chemotaxis of leukocytes to an inflammatory site in mink is comparable to that observed was reduced in the affected animals. in humans with the Chediak-Higashi In vitro studies documented a cons...
متن کاملDefective granulocyte chemotaxis in the Chediak-Higashi syndrome.
In vivo and in vitro studies of granulocyte chemotaxis were performed in three patients with the Chediak-Higashi syndrome. Rebuck skin windows showed a decreased accumulation of leukocytes at an inflammatory site. Studies in Boyden chambers documented a cellular defect in granulocyte chemotaxis. The chemotactic response of Chediak-Higashi cells by this technique averaged approximately 40% of no...
متن کاملChediak-Higashi Syndrome
Impaired vision Photophobia Albinism of the OCA2 type, giving a lighter complexion than unaffected family members [6] Silvery sheen to hair which may be fair in colour Frequent infections (skin, mucous membranes, respiratory) Epilepsy Mental retardation Enlarged liver and spleen Jaundice Ataxia causing incoordination and a typical ataxic gait Tremor Epilepsy Peripheral neuropathy causing motor ...
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ژورنال
عنوان ژورنال: Blood
سال: 1974
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v43.2.201.201